Evalution Of Antioxidant Activities Of Selected Indian Plants
Evalution Of Antioxidant Activities Of Selected Indian Plants
M. P. Dobhal1, M. C. Sharma1, S. Rao1, N. Agrawal1 and V. Mangal2
1Natural Products Laboratory, Department of Chemistry, University of Rajasthan, Jaipur
2Birla Institute of technology, Mesra, Ranchi
ABSTRACT:
The methanolic extracts of seeds of Ipomoea hederacea (Convolvulaceae) and Strychnos potatorum
(Loganiacea), leaves of Zanthoxylum alatum (Rutaceae) and stem bark of Alstonia scholaris (Apocynaceae)
were subjected to evaluation of antioxidant potential by using DPPH method. Out of these selected
plants Zanthoxylum alatum was found to show maximum antioxidant potential. Whereas methanolic
extracts of Alstonia scholaris and Strychnos potatorum were found to show moderate antioxidant potential.
INTRODUCTION:
It was suggested recently that generation of free radicals play a major role in the progression of a
wide range of pathological disturbances such as brain dysfunction, cancer and cardiovascular diseases1,2.
Free radicals, together with other derivatives of oxygen are inevitable by products of biological redox
reactions. Reactive oxygen species such as superoxide anion (O2-), hydroxyl radical (OH.) and nitric
oxide inactivates enzymes and damage important cellular components causing tissue injury through
covalent binding and lipid peroxidation and thus have been shown to augment collagen synthesis and
fibrosis. Antioxidants are supposed to protect cell membranes against free radical oxidative damages3,4.
The synthetic antioxidants may create health problems. So scientists have focused on isolation and
characterization of natural antioxidants. The natural antioxidants have replaced the synthetic ones
because they are beneficial for our health and they are soluble in oil and water. There is growing
interest to replace synthetic antioxidants by natural...
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